Locally dynamic synaptic learning rules in pyramidal neuron dendrites
نویسندگان
چکیده
منابع مشابه
Location-Dependent Excitatory Synaptic Interactions in Pyramidal Neuron Dendrites
Neocortical pyramidal neurons (PNs) receive thousands of excitatory synaptic contacts on their basal dendrites. Some act as classical driver inputs while others are thought to modulate PN responses based on sensory or behavioral context, but the biophysical mechanisms that mediate classical-contextual interactions in these dendrites remain poorly understood. We hypothesized that if two excitato...
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How effectively synaptic and regenerative potentials propagate within neurons depends critically on the membrane properties and intracellular resistivity of the dendritic tree. These properties therefore are important determinants of neuronal function. Here we use simultaneous whole-cell patch-pipette recordings from the soma and apical dendrite of neocortical layer 5 pyramidal neurons to direc...
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ژورنال
عنوان ژورنال: Nature
سال: 2007
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature06416